Nguoi benh chau A can than trong voi thuoc Crestor

Vao tuan roi, hom 3/3, FDA da canh bao cac bac sy can than trong khi ke don thuoc Crestor cho nhung benh nhan la nguoi chau A. Crestor la ten cua mot loai thuoc tri chung tang cholesterol mau va duoc ban rong rai tren the gioi. Benh nhan nguoi chau A su dung thuoc nay chi duoc uong voi lieu thap nhat 5 mg/ngay, lieu toi da la 40 mg/ngay

Ke tu khi thuoc Crestor duoc tung ra thi truong vao thang 8 nam 2003, da co hon 4,3 trieu nguoi tren the gioi dung thuoc. Voi hoat dong quang cao ram ro, nam ngoai, doanh thu toan cau cua thuoc Crestor dat 908 trieu do la. Rieng tai VN, theo thong tin cong bo tu Cuc Quan ly duoc (Bo Y te), Crestor duoc nhap vao VN do cong ty Astra Zeneca Singapore dang ky. Con nha san xuat la Cong ty IPR Pharmaceuticals. Thuoc duoc ban o VN duoi dang vien nen bao phim 20mg. Gia ban le khoang 18.000 dong/vien

FDA xac nhan, trong thuc te co nhung benh nhan dung thuoc Crestor va cac thuoc cung loai co chua hoat chat statin da bi mac benh than. Tuy nhien, FDA cho biet thuong la nhieu nguoi trong so nhung benh nhan dung nhung loai thuoc nay neu da mac benh dai duong, tang huyet ap hoac benh tim cung co nguy co bi benh than. Song, FDA cam doan rang nhung thuoc nay khi duoc dung dung nhu bac sy ke don thi co hieu qua lon hon nhieu so voi nhung nguy co tiem an.

Khuyen cao cua FDA bat nguon tu nghien cuu cua hang duoc pham AstraZeneca (hang san xuat thuoc Crestor). Nghien cuu cho thay benh nhan o chau A hap thu thuoc nay khac voi benh nhan o My von phan lon la nguoi da trang. Su khac biet nay co the la do anh huong moi truong song nhu che do an gay bat loi cho gien. Benh nhan chau A chi can mot nua lieu tieu chuan la co tac dung ha cholesterol. Neu dung ca lieu se co nguy co bi hieu ung phu. Con nhung benh nhan khac khong nen dung lieu toi da do thuoc co the gay hai co dan den tu vong.

Song gioi y hoc chua biet ro lieu benh nhan nguoi chau A song o My se phan ung the nao voi thuoc Crestor. Do do, FDA yeu cau hang san xuat can tien hanh nghien cuu them ve van de nay. Con ong David Brennan, chu tich hang AstraZeneca khang dinh, thuoc Crestor an toan va hieu qua neu duoc su dung dung lieu.