Benh dau tuy xuong

Tags: roi loan chuc nang, ung thu xuong, Tuy xuong, ton thuong, te bao, bieu hien, mien dich, khoi u, benh, tang, mau, giam, tieu
Benh dau tuy xuong

Dau tuy xuong, con goi la benh Kahler, la dang ung thu xuong hay gap nhat. Khoi u (co nguon goc tu tuy xuong) va nhung san pham cua no gay roi loan chuc nang, khien nguoi benh co bieu hien dau xuong, suy than, de nhiem trung...

Benh dau tuy xuong thuong gap o nong dan, nguoi don cui, cong nhan thuoc da, nhung nguoi tiep xuc voi san pham dau lua. Benh thuc chat la tinh trang tang nhanh ac tinh nhung tuong bao (te bao plasmocyte) xuat phat tu tuy xuong, san xuat globulin mien dich don dong. Hien nay chua ro nguyen nhan gay benh, song benh co tinh di truyen, bieu hien o nhung roi loan ve nhiem sac the va gene. Ngoai ra, benh con lien quan den roi loan te bao mien dich, dac biet la te bao plasma va mien dich the, Interleukin 6.

Bieu hien lam sang

- Ton thuong xuong: do su tang sinh cua nhung te bao u va su hoat hoa cac te bao tieu xuong gay nen. Vi tri ton thuong thuong la xuong so, xuong don, xuong uc, xep dot song dan den hoi chung ep de than kinh cot song. Dau xuong la bieu hien hay gap nhat, chiem 70%.

- Tang canxi mau do hau qua cua su tieu xuong, doi khi gay tinh trang cap cuu.

- Nhiem trung: viem phoi, viem duong tiet nieu… do giam kha nang mien dich.

- Suy than: do tang canxi mau, do ton thuong cau than, tang nhiem toan than vi tang axit uric, su nhiem trung tai phat nhieu lan. Ngoai ra, con ton thuong ong than do co qua nhieu protein trong ong than, bieu hien la protein nieu, giam natri nieu.

- Thieu mau: do su xam lan cua te bao u va tuy uc che chat tao huyet, va do nhung yeu to tai khoi u sinh ra. Ngoai ra con co hien tuong tan huyet nhe, thieu mau hong cau to, giam bach cau hat va giam tieu cau.

- Trieu chung than kinh: tuy it gap, song co bieu hien nhu met moi, roi loan thi giac, benh ly vong mac. Ton thuong xep dot song se gay nen ep tuy, dau kieu re, dai tieu tien khong tu chu vi mat kha nang kiem soat bang quang va duong ruot. Benh ly da day than kinh va giac quan van dong, hoi chung ep tuy do gay xuong benh ly.

- Chay mau: do roi loan chuc nang tieu cau, ton thuong noi mach.

- Mac du te bao plasma co o khap noi trong co the, song khoi u lan chu yeu vao xuong va tuy. Doi khi hach to lach to, gan to.

Xet nghiem:

- Mau: thieu mau, giam bach cau, giam tieu cau, tang toc do mau lang, thieu hut dong mau, giam chuc nang tieu cau, tang do nhot cua mau.

- Tuy xuong: tuong bao tang tren 15% voi hinh thai khong dien hinh, dang non va nhieu nhan.

- Sinh hoa: thay tang canxi mau, tang axit uric, tang globulin mau, giam albumin mau, tang ure mau, protein nieu.

- Mien dich: dien di protein huyet thanh, 75% benh nhan thay dai don dong IgG 50%, IgA 25%. Dien di nuoc tieu thay chuoi nhe tren 50%. Dien di mien dich co the thay globulin mien dich don dong.

- X-quang thay ton thuong tuy xuong, loang xuong, gay xuong o cac vi tri nhu xuong so, cot song, xuong suon.

Cach chan doan: dua vao ba trieu chung co dien:

- Tang te bao plasma trong tuy xuong (10%)

- Ton thuong tieu xuong

- Co IgM trong nuoc tieu hoac trong huyet thanh

- Trong truong hop khong co ton thuong xuong ma te bao plasmocyte tang sinh trong tuy xuong, viec chan doan van duoc xac dinh.

Dieu tri

- Hoa tri lieu: de kiem soat su tien trien cua benh. Melphalan (hoac Cyclophosphamid, hoac Clorambucil) ket hop voi prednisolon.

- Dieu tri trieu chung, phong nhung bien chung nguy hiem:

+ Tang canxi mau

+Gay xuong

+ Nhiem khuan

- Suy than:

+ Loi tieu, thay huyet tuong, loc mang bung

+ Phat hien va dieu tri som nhiem khuan duong tiet nieu

- Tang do nhot mau, bang cach thay huyet tuong

- Chong thieu mau: bang thuoc co sat, axit forlic.

HN
(Theo ttvn)

Viet Bao

Tìm hiểu: roi loan chuc nang, ung thu xuong, Tuy xuong, ton thuong, te bao, bieu hien, mien dich, khoi u, benh, tang, mau, giam, tieu

Xem Bản Tiếng Việt Có Dấu: Bệnh đau tuỷ xương

Ban co the doc ban tieng Viet co dau cua bai viet Bệnh đau tuỷ xương bang cach nhan chuot vao duong dan tren.

Lien he ve tin Benh dau tuy xuong

Nhan xet, hay lien he ve tin Benh dau tuy xuong co the gui bang duong dan o duoi. Ban nen gui kem tieu de bai viet Benh dau tuy xuong de lam tham khao. Bai viet nay thuoc chuyen de Tin suc khoe trong chuyen muc Suc khoe.

Cac tin khac:

Xem tiep ... Tin suc khoe
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